Cell cycle regulation in Trypanosoma brucei

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منابع مشابه

The cell cycle and cytoskeletal morphogenesis in Trypanosoma brucei.

I . Hayes, J. I). & Wolf. C. R. ( IYSX) in Ghituthione (’onjugation (Sies, H. & Ketterer. 8.. eds), pp. 315-355. Academic Press Limited, London 2. Meister. A. ( 1980) in Ghrtrithione: Chemicul, Biochemical, mid Medical Aspc~rts (Dolphin, D.. Poulson. R. & Avramovic, 0.. A), pp. 307-474, John Wiley & Sons. New York 3. Kramer, R. A,, Zakher, J. & Kim, G. (1988) Science 241, 604-696 -1. Riirlamh. ...

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The Cell Cycle Regulated Transcriptome of Trypanosoma brucei

Progression of the eukaryotic cell cycle requires the regulation of hundreds of genes to ensure that they are expressed at the required times. Integral to cell cycle progression in yeast and animal cells are temporally controlled, progressive waves of transcription mediated by cell cycle-regulated transcription factors. However, in the kinetoplastids, a group of early-branching eukaryotes inclu...

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Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei.

Rab proteins are small GTPases that control the direction and timing of vesicle fusion during intracellular trafficking between membraneous compartments. Genome sequencing and EST analysis of Trypanosoma brucei indicates that the trypanosome Rab (TbRAB) gene family, and hence complexity of intracellular transport pathways, is intermediate between Saccharomyces cerevisiae and mammals. TbRAB31 is...

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Trypanosoma brucei brucei

Protein synthesis in Trypanosoma brucei brucei was rapidly inhibited during polyamine depletion by DL-adifluoromethylornithine (DFMO) in vitro and in vivo. [3H]Leucine incorporation was depressed 30-40 % by 24 h and 80-90 % by 48 h of DFMO treatment. Concomitantly there was an apparent decrease in the synthesis of the variant-specific glycoprotein (VSG) in DFMO-treated trypanosomes, as measured...

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Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions

The cell shape of Trypanosoma brucei is influenced by flagellum-to-cell-body attachment through a specialised structure - the flagellum attachment zone (FAZ). T. brucei exhibits numerous morphological forms during its life cycle and, at each stage, the FAZ length varies. We have analysed FLAM3, a large protein that localises to the FAZ region within the old and new flagellum. Ablation of FLAM3 ...

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ژورنال

عنوان ژورنال: Molecular and Biochemical Parasitology

سال: 2007

ISSN: 0166-6851

DOI: 10.1016/j.molbiopara.2007.01.017